Harry J M Groen Selected Research

rociletinib

2/2021

Efficacy and Safety of Rociletinib Versus Chemotherapy in Patients With EGFR-Mutated NSCLC: The Results of TIGER-3, a Phase 3 Randomized Study.

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Harry J M Groen Research Topics

Disease

83	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 11/2002
62	Neoplasms (Cancer) 01/2024 - 02/2002
28	Lung Neoplasms (Lung Cancer) 01/2024 - 05/2004
15	Disease Progression 02/2021 - 04/2009
12	Chronic Obstructive Pulmonary Disease (COPD) 05/2024 - 03/2010
12	Neoplasm Metastasis (Metastasis) 05/2023 - 02/2003
8	Brain Neoplasms (Brain Tumor) 01/2022 - 01/2016
5	Emphysema 04/2023 - 02/2014
5	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2021 - 06/2006
4	Circulating Neoplastic Cells 12/2019 - 07/2015
4	Hypoxia (Hypoxemia) 01/2017 - 12/2012
3	Adenocarcinoma of Lung 11/2021 - 01/2016
3	Fatigue 01/2021 - 11/2017
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 05/2013
3	Pain (Aches) 01/2021 - 02/2013
2	Cough 01/2023 - 01/2021
2	Sarcoma (Soft Tissue Sarcoma) 04/2021 - 08/2013
2	Diarrhea 02/2021 - 11/2017
2	Vomiting 02/2021 - 10/2017
2	Neutropenia 01/2021 - 01/2019
2	Malignant Mesothelioma 01/2021 - 05/2013
2	Thrombocytopenia (Thrombopenia) 01/2019 - 08/2004
2	Adenocarcinoma 01/2018 - 01/2011
2	Mesothelioma 01/2017 - 05/2013
2	Pneumonia (Pneumonitis) 06/2005 - 05/2004
2	Radiation Pneumonitis 05/2004 - 07/2003
1	Retinoblastoma (Glioblastoma, Retinal) 01/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Leukopenia 10/2021
1	Hyperglycemia 02/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Infections 01/2021
1	Asthenia 01/2021

Drug/Important Bio-Agent (IBA)

15	Biomarkers (Surrogate Marker)IBA 01/2024 - 08/2005
12	ErbB Receptors (EGF Receptor)IBA 04/2023 - 06/2010
12	Erlotinib Hydrochloride (CP 358,774)FDA Link 10/2022 - 06/2010
10	Tyrosine Kinase InhibitorsIBA 04/2023 - 08/2013
10	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 08/2004
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2002
9	PlatinumIBA 02/2021 - 06/2002
8	Gemcitabine FDA Link 02/2021 - 07/2003
7	DNA (Deoxyribonucleic Acid)IBA 03/2022 - 01/2017
7	CrizotinibIBA 01/2020 - 02/2015
6	Circulating Tumor DNAIBA 08/2023 - 10/2018
6	Pemetrexed (MTA)FDA Link 02/2021 - 04/2009
6	Bevacizumab (Avastin)FDA Link 01/2019 - 01/2011
5	Docetaxel (Taxotere)FDA Link 10/2021 - 08/2004
5	Paclitaxel (Taxol)FDA LinkGeneric 02/2021 - 11/2007
5	AfatinibIBA 11/2020 - 09/2014
5	Cisplatin (Platino)FDA LinkGeneric 11/2017 - 06/2002
4	Cell-Free Nucleic AcidsIBA 08/2023 - 01/2015
4	RNA (Ribonucleic Acid)IBA 05/2023 - 01/2015
4	Anaplastic Lymphoma KinaseIBA 01/2022 - 02/2015
4	Etoposide (VP 16)FDA LinkGeneric 01/2021 - 11/2007
4	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2021 - 04/2006
4	Gefitinib (Iressa)FDA Link 11/2020 - 09/2014
4	dabrafenibIBA 01/2020 - 01/2016
4	Phosphotransferases (Kinase)IBA 01/2017 - 06/2010
3	GoldIBA 03/2024 - 01/2013
3	Messenger RNA (mRNA)IBA 05/2023 - 09/2013
3	osimertinibIBA 04/2023 - 01/2020
3	Tobacco Smoke Pollution (Passive Smoking)IBA 12/2022 - 04/2020
3	brigatinibIBA 09/2022 - 08/2017
3	Immune Checkpoint InhibitorsIBA 11/2021 - 12/2018
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2011
3	trametinibIBA 01/2020 - 07/2016
3	RadiopharmaceuticalsIBA 01/2017 - 02/2002
3	CalciumIBA 01/2015 - 12/2010
2	AsbestosIBA 05/2024 - 01/2022
2	B7-H1 AntigenIBA 01/2024 - 10/2019
2	capmatinibIBA 01/2023 - 01/2020
2	ORALIT (ORS)IBA 01/2022 - 04/2020
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021 - 01/2019
2	veliparibIBA 01/2021 - 01/2019
2	ParaffinIBA 10/2020 - 08/2013
2	Formaldehyde (Formol)FDA Link 10/2020 - 08/2013
2	LigandsIBA 12/2018 - 08/2003
2	Epithelial Cell Adhesion MoleculeIBA 10/2018 - 07/2015
2	Cetuximab (Erbitux)FDA Link 11/2017 - 09/2014
2	fluoroazomycin arabinosideIBA 11/2014 - 08/2013
2	Sorafenib (BAY 43-9006)FDA Link 02/2013 - 06/2010
2	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2013 - 03/2010
2	Angiogenesis InhibitorsIBA 01/2011 - 08/2005
2	Epirubicin (Ellence)FDA LinkGeneric 06/2010 - 05/2004
2	2',2'-difluoro-2'-deoxyuridineIBA 06/2010 - 06/2010
1	Bronchodilator Agents (Bronchodilators)IBA 03/2024
1	NivolumabIBA 05/2023
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 04/2021
1	erythromycin propionate-N-acetylcysteinateIBA 04/2021
1	rociletinibIBA 02/2021
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	FluorineIBA 01/2021

Therapy/Procedure

31	Therapeutics 01/2024 - 12/2003
21	Drug Therapy (Chemotherapy) 10/2022 - 12/2003
14	Radiotherapy 01/2021 - 07/2003
7	Immunotherapy 01/2024 - 01/2017
4	Cranial Irradiation 01/2022 - 10/2018
3	Thoracotomy 02/2013 - 04/2006
2	Adjuvant Chemotherapy 01/2019 - 02/2013
1	Combination Drug Therapy (Combination Chemotherapy) 01/2024